If you’re looking for the perfect comfort food that combines savory, creamy, and downright satisfying flavors, look no further than this Chicken and Stuffing Casserole. It’s one of those cozy dishes that feels like a warm hug on a cold night. Whether you’re cooking for family dinner, a potluck, or just meal-prepping for the week, this dish is a total crowd-pleaser.
The best part? It’s simple, hearty, and uses everyday ingredients that are easy to find. With tender chunks of chicken, flavorful stuffing, and a creamy sauce that ties everything together, this casserole is the ultimate comfort classic.
You can prep everything in one pan with minimal cleanup. It’s also perfect for using up leftover chicken or turkey. Even picky eaters love this one — it’s got all the cozy notes of Thanksgiving in every bite!
This recipe is budget-friendly, family-approved, and ridiculously easy to customize. Get ready to fall in love with your new favorite dinner!
What Makes This Chicken and Stuffing Casserole Special?
- One-dish wonder: Everything bakes in a single dish — less mess, less stress.
- Quick prep: Just 15 minutes of hands-on time, then let the oven do the work.
- Versatile: Works with rotisserie chicken, leftover turkey, or even canned chicken.
- Cozy and comforting: Feels like Thanksgiving, but it’s easy enough for weeknights.
- Crowd-pleaser: Loved by adults and kids alike — great for family meals or potlucks.
Bonus tip: Use store-bought stuffing mix to save time without sacrificing flavor!
Ingredient Notes
- Cooked chicken: Use shredded rotisserie, leftover roasted chicken, or poached chicken breasts. Turkey works too.
- Stuffing mix: Boxed stuffing mix like Stove Top is perfect for this. Choose herb-seasoned for extra flavor.
- Cream of chicken soup: Adds richness and creaminess. Sub with cream of mushroom or homemade white sauce if preferred.
- Sour cream: Adds tang and balances the richness. Greek yogurt is a great substitute.
- Chicken broth: Helps moisten the stuffing. Can also use vegetable broth.
- Butter: Adds flavor and helps brown the topping. Margarine works in a pinch.
- Seasonings: Salt, pepper, garlic powder — keep it simple, but feel free to spice it up.
Optional equipment: A 9×13-inch baking dish, mixing bowl, spatula.
How To Make Chicken and Stuffing Casserole
- Preheat the oven to 375°F (190°C) and grease a 9×13-inch baking dish.
- Prepare the stuffing mix: Follow package instructions using the chicken broth instead of water for more flavor. Set aside.
- Mix the creamy filling: In a large bowl, stir together cream of chicken soup, sour cream, seasonings, and cooked chicken until well combined.
- Assemble the casserole:
- Spread the creamy chicken mixture into the greased baking dish.
- Spoon the stuffing evenly over the top.
- Dot with butter (this helps get a crispy golden top).
- Bake for 35–40 minutes, or until hot and bubbly and the top is golden brown.
Tip: Let it rest for 5 minutes before serving — it thickens slightly and becomes easier to scoop.
Storage Options
- Room temperature: Not recommended beyond 2 hours.
- Refrigerate: Store leftovers in an airtight container for up to 4 days.
- Freeze: Wrap tightly in foil or freezer-safe container for up to 2 months. Thaw overnight before reheating.
- Reheat: Warm in the oven at 350°F or microwave individual portions. Add a splash of broth to keep it moist.
Variations and Substitutions
- Vegetarian: Use cream of mushroom soup and replace chicken with sautéed mushrooms and spinach.
- Cheesy: Add 1 cup of shredded cheddar or mozzarella to the creamy mixture.
- Low-carb: Swap stuffing with roasted cauliflower florets and a sprinkle of almond flour.
- Holiday twist: Add dried cranberries and chopped pecans to the stuffing mix.
- Spicy: Mix in diced green chiles or a dash of hot sauce for a kick.
Frequently Asked Questions
Can I make this ahead of time? Yes! Assemble the dish, cover, and refrigerate up to 24 hours in advance. Bake when ready.
Can I use canned chicken? Absolutely. Just drain it well and fluff it with a fork before mixing.
What if I don’t have sour cream? Greek yogurt, cream cheese, or even mayo can work in a pinch.
Can I add vegetables? Totally. Stir in frozen peas, diced carrots, or green beans for extra nutrition.
Why is my casserole dry? Make sure your stuffing is moistened well before baking and don’t skip the broth or butter.
Is this dish freezer-friendly? Yes! Freeze unbaked or baked portions. Wrap tightly and label with date.
Conclusion
There’s nothing like a homemade Chicken and Stuffing Casserole to bring people together. It’s the kind of meal that feels like home — warm, simple, and comforting. Whether you’re making it from scratch or using up leftovers, this dish always delivers big flavor with minimal effort.
If you try this recipe, leave a comment below or tag your dish on social media — I’d love to see your version. Happy cooking!
Chicken and Stuffing Casserole Recipe (Ultimate Comfort Food!)
- Prep Time: 15 minutes
- Cook Time: 40 minutes
- Total Time: 55 minutes
- Yield: 6 servings 1x
Ingredients
- 3 cups cooked chicken, shredded
- 1 box stuffing mix (6 oz)
- 1 can cream of chicken soup (10.5 oz)
- 1/2 cup sour cream
- 1 cup chicken broth
- 2 tablespoons butter, diced
- 1/2 teaspoon garlic powder
- Salt and pepper to taste
Instructions
- Preheat oven to 375°F and grease a 9×13 baking dish.
- Prepare stuffing using broth.
- Mix chicken, soup, sour cream, and seasonings.
- Spread chicken mix in dish, top with stuffing, dot with butter.
- Bake 35–40 min until golden and bubbly. Rest before serving.
Notes
Add cheese or veggies for a twist. Freezes well.
Nutrition
- Calories: ~410
- Sodium: ~900mg
- Fat: 20g
- Carbohydrates: 26g
- Fiber: 2g
- Protein: 27g